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Mouse Anti-Canine Interleukin 10 (IL10) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine interleukin 10. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine interleukin 10.
Specifications
Target Information
Canine interleukin 10 (IL-10) is a critical anti-inflammatory cytokine primarily produced by monocytes and lymphocytes. It plays a significant role in immunoregulation and inflammation by down-regulating the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. IL-10 also enhances B cell survival, proliferation, and antibody production, while blocking NF-kappa B activity and regulating the JAK-STAT signaling pathway. This cytokine is essential in maintaining a balanced immune response and has been associated with the pathogenesis of various diseases in dogs, including leishmaniasis, where it can promote parasite replication and disease progression.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.