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Mouse Anti-Porcine Spectrin Beta Chain (SPTBN1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for spectrin beta chain. It is affinity purified by protein G. It can be applied to WB, IHC and ELISA assays of spectrin beta chain.
Specifications
Target Information
Porcine spectrin beta chain (pSPTB) is a vital component of the spectrin protein family, which forms the backbone of the cytoskeleton in cells. This protein is particularly abundant in red blood cells, where it contributes to maintaining cell shape and membrane integrity. As part of the spectrin-actin network, pSPTB plays a critical role in determining the mechanical properties of the cell membrane, providing both flexibility and stability. pSPTB is involved in various cellular functions, including the regulation of cell volume, protection against mechanical stress, and the organization of membrane proteins. It interacts with other cytoskeletal elements and membrane-associated proteins, contributing to the complex architecture of the cell cortex.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Gallagher, Patrick G., et al. "A splice site mutation of the beta-spectrin gene causing exon skipping in hereditary elliptocytosis associated with a truncated beta-spectrin chain." Journal of Biological Chemistry 266.23 (1991): 15154-15159.