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Rabbit Anti-Bovine Parathyroid Hormone (PTH) Polyclonal Antibody

Cat. No.VD11N330

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine parathyroid hormone. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine parathyroid hormone.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone D23N2
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Parathyroid Hormone
Immunogen Recombinant protein of parathyroid hormone
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine parathyroid hormone (bPTH) is a potent regulator of calcium metabolism and bone homeostasis. It acts as a ligand for the parathyroid hormone 1 receptor (PTH1R), which is crucial in mediating the actions of PTH and PTH-related peptide (PTHrP) in mammals. bPTH enhances osteoclast bone resorption by modulating the vacuolar-type H+ adenosine triphosphatase (V-ATPase), which plays a key role in cellular acidification and bone resorption. This direct effect on osteoclasts and osteoblasts contributes to bone remodeling, making PTH1R a significant target in the context of bPTH's function.

Target Bovine Parathyroid Hormone
Target Synonym PTH; Parathyrin
Gene ID 280903
UniProt ID P01268

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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