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Rabbit Anti-Bovine Parathyroid Hormone (PTH) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine parathyroid hormone. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine parathyroid hormone.
Specifications
Target Information
Bovine parathyroid hormone (bPTH) is a potent regulator of calcium metabolism and bone homeostasis. It acts as a ligand for the parathyroid hormone 1 receptor (PTH1R), which is crucial in mediating the actions of PTH and PTH-related peptide (PTHrP) in mammals. bPTH enhances osteoclast bone resorption by modulating the vacuolar-type H+ adenosine triphosphatase (V-ATPase), which plays a key role in cellular acidification and bone resorption. This direct effect on osteoclasts and osteoblasts contributes to bone remodeling, making PTH1R a significant target in the context of bPTH's function.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.