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Mouse Anti-Swine CD46 Monoclonal Antibody
Product Overview
O11H22 monoclonal antibody is specific for Swine CD46, also know as Swine AHUS2 or MCP . It was purified by affinity chromatography on Protein G from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Immunoprecipitation (IP) and Western Blot (WB).
Specifications
Target Information
Cluster of differentiation 46 (CD46) is a type I transmembrane glycoprotein that is expressed on most tissues as four major isoforms (BC1, BC2, C1 and C2) that arise from alternative splicing of a single gene. CD46 plays a major role in regulating T cell-induced inflammatory reaction and in fine-tuning the cellular immune response by bridging innate and acquired immunity. Swine CD46 plays a major role in the initial steps of Classical swine fever virus infection.
Shipping and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
References
- Lamothe-Reyes, Yaneysis, et al. "Host cell factors involved in classical swine fever virus entry." Veterinary Research 54.1 (2023): 115.