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Mouse Anti-Canine Lysine-Specific Demethylase 5C (SMCX) Monoclonal Antibody

Cat. No.VD12N424

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine lysine-specific demethylase 5C. It is purified by affinity chromatography. It can be applied to WB and IF assays of canine lysine-specific demethylase 5C.

Specifications

Application WB; IF
Clonality Monoclonal
Classification Primary Antibody
Clone M5N38
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Lysine-Specific Demethylase 5C
Immunogen Recombinant protein of lysine-specific demethylase 5C
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer 0.1M Tris-Glycine, pH 7.4, with 150 mM NaCl and 50% glycerol
Physical State Liquid

Target Information

Canine Lysine-Specific Demethylase 5C (KDM5C), also known as JARID1C or SMCX, is a histone demethylase that specifically targets trimethylated and dimethylated lysine 4 on histone H3 (H3K4me3/me2), playing a crucial role in epigenetic regulation of gene expression. It is involved in transcriptional repression and chromatin remodeling, and its dysfunction has been implicated in X-linked neurodevelopmental disorders. KDM5C is also involved in the regulation of circadian rhythms and has been identified as a potential therapeutic target in cancer.

Target Canine Lysine-Specific Demethylase 5C
Target Synonym SMCX; KDM5C
Gene ID 491894
UniProt ID Q38JA7

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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