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Mouse Anti-Chicken Tubulin Beta Monoclonal Antibody-[HRP]
Product Overview
BioVenic mouse monoclonal antibody is specific for chicken tubulin beta. It can be applied to WB, IF, ICC and IHC assays of chicken tubulin beta.
Specifications
Target Information
Beta-tubulin, a subunit of the tubulin family, is a critical structural protein that heterodimerizes with alpha-tubulin to form the microtubules essential for a myriad of cellular processes. These microtubules serve as the cellular scaffold, facilitating intracellular transport, maintaining cell shape, and segregating chromosomes during cell division. Beta-tubulin is highly conserved across eukaryotic organisms, reflecting its fundamental role in cell biology. The dynamic nature of microtubules, characterized by their rapid assembly and disassembly, is regulated by various cellular signals and environmental cues. Beta-tubulin, along with alpha-tubulin, is a target for several antimitotic drugs used in cancer therapy, such as taxanes and vinca alkaloids, which stabilize or disrupt microtubules, respectively, leading to the inhibition of cell proliferation.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Díaz-Nido, Javier, et al. "Phosphorylation of a neuronal-specific beta-tubulin isotype." Journal of Biological Chemistry 265.23 (1990): 13949-13954.