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Mouse Anti-Porcine Insulin Receptor Substrate 1 (IRS1) Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine insulin receptor substrate 1. It is purified by affinity chromatography. It can be applied to WB assay of porcine insulin receptor substrate 1.

Specifications

Application WB

Clonality Monoclonal

Classification Primary Antibody

Clone M4N38

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Porcine Insulin Receptor Substrate 1

Isotype IgG

Immunogen Synthesized peptide of insulin receptor substrate 1

Purification Purified by Affinity Chromatography

Concentration 1 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline with 50% Glycerol and 0.5% BSA

Physical State Liquid

Target Information

Porcine Insulin Receptor Substrate 1 (IRS-1) is a key signaling molecule involved in insulin and IGF-1 receptor pathways, mediating metabolic and mitogenic responses. It acts as an adaptor protein, facilitating the recruitment of downstream signaling molecules such as PI3K and Akt. IRS-1 is heavily phosphorylated on tyrosine and serine residues, which regulate its activity and downstream signaling.

Target Porcine Insulin Receptor Substrate 1

Target Synonym IRS1

Gene ID 100512686

UniProt ID I3LLF1

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wu, Di, et al. "miR-146a-5p inhibits TNF-α-induced adipogenesis via targeting insulin receptor in primary porcine adipocytes." Journal of lipid research 57.8 (2016): 1360-1372.