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Rabbit Anti-Canine IL-2 Monoclonal Antibody
Product Overview
BioVenic is specific for canine IL-2. It was produced in rabbit hybridoma and protein A purified. It can be applied to ELISA assay.
Specifications
Target Information
Canine IL-2 (interleukin-2), an essential growth factor in the immune system, is highly expressed in the lymph nodes of dogs with Leishmaniasis. The function of IL-2 includes enabling growth factor activity and interleukin-2 receptor binding. It's involved in the immune response and is located in the extracellular region. Also, IL-2 plays a key role in the balance of IL-12/IL4 in renal tissue which regulates the inflammatory response in Leishmania-infected dogs. Moreover, studies have compared the immunoreactivities of molecules like IL-2 and its receptor (IL-2R), in the cervical and lumbar spinal cord of young and aged beagle dogs.
Shipping and Storage
This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Haagsman, Annika N., et al. "The effect of interleukin-2 on canine peripheral nerve sheath tumours after marginal surgical excision: a double-blind randomized study." BMC veterinary research 9 (2013): 1-8.