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Rabbit Anti-Bovine Aggrecan Core Protein (ACAN) Polyclonal Antibody

Cat. No.VD12N275

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine aggrecan core protein. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine aggrecan core protein.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone F22N26
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Aggrecan Core Protein
Immunogen Recombinant protein of aggrecan core protein
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine aggrecan core protein (ACAN) is a major component of the extracellular matrix in cartilaginous tissues, encoded by the ACAN gene. It is a large proteoglycan that resists compression in cartilage by binding to hyaluronic acid through its N-terminal globular region. This protein is essential for maintaining cartilage integrity and function, making it a critical target in studies related to joint health and cartilage degeneration.

Target Bovine Aggrecan Core Protein
Target Synonym ACAN
Gene ID 280985
UniProt ID P13608

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Hedlund, Håkan, et al. "Association of the aggrecan keratan sulfate-rich region with collagen in bovine articular cartilage." Journal of Biological Chemistry 274.9 (1999): 5777-5781.
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