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Rabbit Anti-Bovine Caspase 8 (CASP8) Polyclonal Antibody-[FITC]
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine caspase 8. It is antigen affinity purified. It can be applied to WB, IHC and IF/ICC assays of bovine caspase 8.
Specifications
Target Information
Bovine caspase 8 is a key protease involved in both apoptosis and necroptosis, acting as a molecular switch for cell death pathways. It is essential for initiating extrinsic apoptosis by mediating the cleavage and activation of effector caspases such as caspase-3, -6, and -7. Caspase 8 also plays a crucial role in preventing necroptosis by cleaving RIPK1, thereby inhibiting its kinase activity and limiting inflammation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.