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Mouse Anti-Porcine Vinculin Monoclonal Antibody

Cat. No.VD8N193

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for vinculin. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of vinculin.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N6
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Vinculin
Isotype IgG1
Immunogen Recombinant protein of vinculin
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine vinculin, a protein found in pigs, is a critical component of the cytoskeleton that plays a significant role in cell adhesion and the maintenance of cell shape. It is particularly concentrated in areas of cell-cell contact known as adherens junctions, where it helps to anchor the actin cytoskeleton to the cell membrane. Vinculin's ability to bind to both actin filaments and integrin complexes is essential for the transmission of mechanical forces within cells and across the extracellular matrix. This protein is highly conserved across species, indicating its fundamental importance in cell biology. In pigs, vinculin's role extends to muscle physiology, where it contributes to the structural integrity of muscle fibers, which is vital for the animal's movement and overall health. Additionally, its involvement in cell adhesion makes it a potential target for research into conditions that affect tissue integrity and wound healing.

Target Vinculin
Target Synonym CMD1W; Metavinculin
Gene ID 396974
UniProt ID P36976

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Bays, Jennifer L., et al. "Vinculin in cell-cell and cell-matrix adhesions." Cellular and Molecular Life Sciences 74 (2017): 2999-3009.
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