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Mouse Anti-Porcine Vinculin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for vinculin. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of vinculin.
Specifications
Target Information
Porcine vinculin, a protein found in pigs, is a critical component of the cytoskeleton that plays a significant role in cell adhesion and the maintenance of cell shape. It is particularly concentrated in areas of cell-cell contact known as adherens junctions, where it helps to anchor the actin cytoskeleton to the cell membrane. Vinculin's ability to bind to both actin filaments and integrin complexes is essential for the transmission of mechanical forces within cells and across the extracellular matrix. This protein is highly conserved across species, indicating its fundamental importance in cell biology. In pigs, vinculin's role extends to muscle physiology, where it contributes to the structural integrity of muscle fibers, which is vital for the animal's movement and overall health. Additionally, its involvement in cell adhesion makes it a potential target for research into conditions that affect tissue integrity and wound healing.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Bays, Jennifer L., et al. "Vinculin in cell-cell and cell-matrix adhesions." Cellular and Molecular Life Sciences 74 (2017): 2999-3009.