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Mouse Anti-Porcine Peroxiredoxin 6 (PRDX6) Monoclonal Antibody

Cat. No.VD10N154

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for peroxiredoxin 6. It is affinity purified by protein A. It can be applied to WB, IP, IF and Indirect ELISA assays of peroxiredoxin 6.

Specifications

Application WB; IP; IF; Indirect ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone O13N2
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Peroxiredoxin 6
Isotype IgG2
Immunogen Recombinant protein of peroxiredoxin 6
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine peroxiredoxin 6 (PRDX6) is a critical antioxidant enzyme that plays a significant role in maintaining cellular redox balance and protecting cells from oxidative stress. As a member of the peroxiredoxin family, PRDX6 is particularly important for the detoxification of peroxides and the regulation of signaling pathways involved in inflammation and immune responses. In pigs, PRDX6 has been shown to be essential in protecting irradiated cells from oxidative stress and in shaping the senescence-associated cytokine landscape. It contributes to cell survival under stress conditions by neutralizing reactive oxygen species (ROS). The enzyme's activity is regulated through various mechanisms, including changes in phosphorylation, redox status, and oligomerization states.

Target Peroxiredoxin 6
Target Synonym 1 Cys
Gene ID 399538
UniProt ID Q9TSX9

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Arevalo, José A., et al. "The role of peroxiredoxin 6 in cell signaling." Antioxidants 7.12 (2018): 172.
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