Mouse Anti-Canine TCP1 Alpha Monoclonal Antibody

Canine TCP1 alpha, a component of the chaperonin-containing T-complex (TRiC), is crucial for protein folding and cellular proteostasis, particularly in the folding of actin and tubulin, which are vital for cytoskeletal functions. This molecular chaperone complex assists in the folding of newly synthesized proteins, especially within large complexes, and is highly expressed in tissues with high protein synthesis rates, such as the brain and testes. TCP1 Alpha's role in maintaining cellular integrity and its involvement in protein homeostasis pathways make it a significant target in understanding and potentially treating diseases related to protein misfolding and aggregation, such as neurodegenerative disorders and cancer.