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Mouse Anti-Canine Melanoma Antigen Family A1 (MAGE 1) Monoclonal Antibody

Cat. No.VD11N244

Product TypeAnimal-targeted Antibodies

Size 100 μg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine Melanoma Antigen Family A1. It can be applied to ICC/IF, IHC and FACS assays of canine Melanoma Antigen Family A1.

Specifications

Application ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S18N48
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Melanoma Antigen Family A1
Isotype IgG1
Immunogen Recombinant protein of melanoma antigen family A1
Concentration 0.2 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline, 0.05% BSA
Physical State Liquid

Target Information

Canine melanoma antigen family A1 (MAGE-A1) is a member of the MAGE gene family, which is also known as cancer-testis antigens (CTAs) or cancer-germline (CG) genes. MAGE-A1 is primarily expressed in male germline cells and placenta, as well as in various tumor cells, including melanoma. This antigen has been recognized as a potential target molecule for cancer immunotherapy due to its restricted expression in a wide range of cancers and its association with resistance to chemotherapy, metastasis, and cancer cell survival. In dogs, MAGE-A1 has been identified in mammary gland tumors, with expression observed in moderate- and high-grade malignant tumors but not in benign ones.

Target Canine Melanoma Antigen Family A1
Target Synonym MAGE 1
Gene ID 403710

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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