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Mouse Anti-Porcine Copper Metabolism Domain Containing 1 (COMMD1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for copper metabolism domain containing 1. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of copper metabolism domain containing 1.
Specifications
Target Information
Porcine copper metabolism domain containing 1 (COMMD1) is a protein that plays a critical role in copper homeostasis within the cell. It is involved in the regulation of copper uptake, storage, and export, ensuring that copper levels are maintained within a healthy range. COMMD1 is part of a larger family of proteins that contain a copper metabolism (CuM) domain, which is essential for binding and processing copper ions. As a molecular target, COMMD1 is significant due to its involvement in copper metabolism, which is crucial for various cellular functions, including enzyme activity, redox reactions, and cellular signaling. Dysregulation of copper homeostasis has been linked to several diseases, such as Wilson's disease, Menkes disease, and certain neurodegenerative disorders.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Mao, Xicheng, et al. "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." Journal of Biological Chemistry 286.37 (2011): 32355-32365.