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Mouse Anti-Porcine Copper Metabolism Domain Containing 1 (COMMD1) Monoclonal Antibody

Cat. No.VD8N488

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for copper metabolism domain containing 1. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of copper metabolism domain containing 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G10N36
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Copper Metabolism Domain Containing 1
Isotype IgG1
Immunogen Recombinant protein of copper metabolism domain containing 1
Purification Protein G Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine copper metabolism domain containing 1 (COMMD1) is a protein that plays a critical role in copper homeostasis within the cell. It is involved in the regulation of copper uptake, storage, and export, ensuring that copper levels are maintained within a healthy range. COMMD1 is part of a larger family of proteins that contain a copper metabolism (CuM) domain, which is essential for binding and processing copper ions. As a molecular target, COMMD1 is significant due to its involvement in copper metabolism, which is crucial for various cellular functions, including enzyme activity, redox reactions, and cellular signaling. Dysregulation of copper homeostasis has been linked to several diseases, such as Wilson's disease, Menkes disease, and certain neurodegenerative disorders.

Target Copper Metabolism Domain Containing 1
Target Synonym COMMD1
Gene ID 100521368
UniProt ID A0A287AYP3

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Mao, Xicheng, et al. "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding." Journal of Biological Chemistry 286.37 (2011): 32355-32365.
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