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Mouse Anti-Swine CD335 Monoclonal Antibody

Cat. No.VD10H35

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

O12H35 monoclonal antibody is specific for Swine (CD335), also known as natural cytotoxicity triggering receptor 1 (NCR1). It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC) and Immunofluorescence (IF).

Specifications

Application FC; IF

Clonality Monoclonal Antibody

Classification Primary Antibody

Clone O12H35

Host Mouse

Target Species Swine

Species Reactivity Swine

Specificity Swine CD335

Isotype IgG1

Immunogen Fusion protein consisting of the extracellular region of swine CD335

Purification Protein A Purified

Purity ≥ 90% (SDS-PAGE)

Concentration 1.0 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.09% Sodium azide (NaN₃)

Buffer Phosphate buffered saline

Physical State Liquid

Target Information

Cluster of differentiation 335 (CD335), also known as natural cytotoxicity triggering receptor 1 (NCR1) is a 46 kDa type I transmembrane protein characterized by two C2-type Ig-like domain. CD335 is not expressed by all swine NK cells and that CD335 discriminates swine NK cells differing in regard to cytokine production. CD335 plays an important role in the recognition and destruction of tumor cells and in viral and bacterial clearance.

Target Swine CD335

Target Synonym NCR1; LY94; NK-p46; NKP46; natural cytotoxicity triggering receptor 1

Gene ID 100141419

UniProt ID C6L8N7

Shipping and Storage

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

References

Mair, Kerstin H., et al. "Porcine CD3+ NKp46+ lymphocytes have NK-cell characteristics and are present in increased frequencies in the lungs of influenza-infected animals." Frontiers in immunology 7 (2016): 263.