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Mouse Anti-Canine Tubulin Tyrosine Ligase Like 12 (TTLL12) Monoclonal Antibody

Cat. No.VD11N14

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine tubulin tyrosine ligase like 12. It can be applied to WB, ICC/IF, IHC and FACS assays of canine tubulin tyrosine ligase like 12.

Specifications

Application WB; ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S9N14
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Tubulin Tyrosine Ligase Like 12
Isotype IgG1
Immunogen Recombinant protein of tubulin tyrosine ligase like 12
Concentration 0.59 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine tubulin tyrosine ligase like 12 (TTL12) is a member of the TTL family, which is highly conserved across species and possesses both SET-like and TTL-like domains. This suggests potential roles in histone methylation and tubulin tyrosine ligase activities. Altered expression of TTL12 in canine cells can lead to specific changes in H4K20 trimethylation and tubulin detyrosination, which are crucial for cellular processes such as mitosis and chromosome number stability. As a target, canine TTL12 is significant for understanding its non-catalytic functions related to tubulin and histone modifications, which could be linked to its effects on mitosis and chromosome number stability.

Target Canine Tubulin Tyrosine Ligase Like 12
Target Synonym TTLL12
Gene ID 474474
UniProt ID A0A8I3S0J8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Brants, Jan, et al. "Tubulin tyrosine ligase like 12, a TTLL family member with SET-and TTL-like domains and roles in histone and tubulin modifications and mitosis." PloS one 7.12 (2012): e51258.
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