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Mouse Anti-Canine Tubulin Tyrosine Ligase Like 12 (TTLL12) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine tubulin tyrosine ligase like 12. It can be applied to WB, ICC/IF, IHC and FACS assays of canine tubulin tyrosine ligase like 12.
Specifications
Target Information
Canine tubulin tyrosine ligase like 12 (TTL12) is a member of the TTL family, which is highly conserved across species and possesses both SET-like and TTL-like domains. This suggests potential roles in histone methylation and tubulin tyrosine ligase activities. Altered expression of TTL12 in canine cells can lead to specific changes in H4K20 trimethylation and tubulin detyrosination, which are crucial for cellular processes such as mitosis and chromosome number stability. As a target, canine TTL12 is significant for understanding its non-catalytic functions related to tubulin and histone modifications, which could be linked to its effects on mitosis and chromosome number stability.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Brants, Jan, et al. "Tubulin tyrosine ligase like 12, a TTLL family member with SET-and TTL-like domains and roles in histone and tubulin modifications and mitosis." PloS one 7.12 (2012): e51258.