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Rabbit Anti-Chicken Calcitonin (CALCA) Polyclonal Antibody

Cat. No.VD11N409

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for chicken calcitonin. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of chicken calcitonin.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone D25N42
Host Rabbit
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken Calcitonin
Immunogen Recombinant protein of calcitonin
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Chicken calcitonin is a hormone that plays a critical role in regulating calcium metabolism in chickens. It is secreted from the ultimobranchial gland and primarily functions to inhibit bone resorption, thereby decreasing blood calcium levels. Calcitonin in chickens also interacts with the calcitonin receptor (CTR) and calcitonin receptor-like receptor (CLR), which are modulated by receptor activity-modifying proteins (RAMPs). These interactions stimulate the cAMP/PKA and MAPK/ERK signaling pathways, indicating their functional receptor status with Calcitonin showing significant ligand activity at nanomolar concentrations.

Target Chicken Calcitonin
Target Synonym CALCA
Gene ID 396256
UniProt ID P07660

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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