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Rabbit Anti-Chicken Calcitonin (CALCA) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for chicken calcitonin. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of chicken calcitonin.
Specifications
Target Information
Chicken calcitonin is a hormone that plays a critical role in regulating calcium metabolism in chickens. It is secreted from the ultimobranchial gland and primarily functions to inhibit bone resorption, thereby decreasing blood calcium levels. Calcitonin in chickens also interacts with the calcitonin receptor (CTR) and calcitonin receptor-like receptor (CLR), which are modulated by receptor activity-modifying proteins (RAMPs). These interactions stimulate the cAMP/PKA and MAPK/ERK signaling pathways, indicating their functional receptor status with Calcitonin showing significant ligand activity at nanomolar concentrations.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.