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Mouse Anti-Feline CD4 Monoclonal Antibody-[FITC]

Cat. No.VD7N368

Product TypeAnimal-targeted Antibodies

Size 0.5 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for feline CD4. It can be applied to FCM, IHC and IP assays of feline CD4.

Specifications

Application FCM; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L12N36
Host Mouse
Target Species Feline
Species Reactivity Feline
Specificity Feline CD4
Isotype IgG1
Immunogen Feline T cells
Purity > 90%
Concentration 0.5 mg/mL
Conjugation FITC
Preservative and Stabilizer < 0.1% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Feline CD4 is a cell surface glycoprotein that serves as a co-receptor on the surface of T-helper cells within the feline immune system. It is crucial for the proper functioning of these cells, which play a central role in the adaptive immune response. fCD4 aids in the interaction between the T cell receptor (TCR) and the major histocompatibility complex class II (MHC II) molecules on antigen-presenting cells (APCs). This interaction is essential for the activation of T-helper cells, leading to the initiation of downstream signaling pathways that result in T cell proliferation, differentiation, and production of cytokines.

Target Feline CD4
Target Synonym fCD4
Gene ID 493775
UniProt ID P79355

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Murphy, Brian, et al. "FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection." Retrovirology 9 (2012): 1-17.
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