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Mouse Anti-Canine Cytokeratin 8 Monoclonal Antibody

Cat. No.VD11N44

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine cytokeratin 8. It can be applied to WB, ICC/IF and IHC assays of canine cytokeratin 8.

Specifications

Application WB; ICC/IF; IHC
Clonality Monoclonal
Classification Primary Antibody
Clone S9N44
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Cytokeratin 8
Isotype IgG2
Immunogen Recombinant protein of cytokeratin 8
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine cytokeratin 8 (CK8) is a type II keratin that pairs with cytokeratin 18 to form intermediate filaments in simple epithelial cells and many epithelial-derived cancers. It plays a critical role in maintaining cellular structural integrity and is involved in signal transduction and cellular differentiation. CK8 is also important for linking the contractile apparatus to dystrophin at the costameres of striated muscle. In veterinary medicine, CK8 can be used as a diagnostic marker for certain tumors due to changes in cytokeratin expression as a result of tumorigenesis. Its expression patterns are valuable for comparative histology and for investigating similarities and differences in cytokeratin expression between normal and neoplastic epithelia in dogs.

Target Canine Cytokeratin 8
Target Synonym Keratin-8; Type-II keratin Kb8
Gene ID 486513
UniProt ID A0A8C0PN02

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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