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Rabbit Anti-Feline Colony Stimulating Factor 1 Receptor (CSF1R) Polyclonal Antibody-[FITC]
Product Overview
BioVenic rabbit polyclonal antibody is specific for feline colony stimulating factor 1 receptor. It is affinity purified by protein G. It can be applied to ELISA assay of feline colony stimulating factor 1 receptor.
Specifications
Target Information
Feline colony stimulating factor 1 receptor (CSF1R) is a cell surface glycoprotein encoded by the CSF1R gene, primarily expressed on mononuclear phagocytes, including monocytes, macrophages, and dendritic cells. It plays a crucial role in the growth, proliferation, and differentiation of these cells during immune responses. CSF1R signaling regulates the differentiation of myeloid cells toward an M2 phenotype of macrophage, which within the tumor microenvironment promotes survival, proliferation, and metastatic potential of tumor cells, along with suppressing antitumor immunity.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Gow, Deborah J., et al. "Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34)." Cytokine 61.2 (2013): 630-638.