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Mouse Anti-Equine IgGb Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for equine IgGb. It is affinity purified by protein A. It can be applied to ELISA assay of equine IgGb.
Specifications
Target Information
Equine IgGb is a subclass of immunoglobulin G (IgG) in horses, playing a significant role in the immune response. IgGb is one of the four major IgG subclasses in horses, which collectively represent the principal immunoglobulins found in plasma, accounting for up to 80% of the total immunoglobulin concentration. IgGb, along with other IgG subclasses, is involved in various immune functions such as opsonization, neutralization, and complement fixation. Specifically, IgGb is effective in fixing complement and participating in antibody-dependent cellular cytotoxicity (ADCC), which are crucial for pathogen clearance and immune defense.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lewis, Melanie J., et al. "The different effector function capabilities of the seven equine IgG subclasses have implications for vaccine strategies." Molecular immunology 45.3 (2008): 818-827.