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Rabbit Anti-Bovine Dopa Decarboxylase Polyclonal Antibody

Cat. No.VD7N387

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine Dopa decarboxylase. It can be applied to IHC and WB of bovine Dopa decarboxylase.

Specifications

Application IHC; WB

Clonality Polyclonal

Classification Primary Antibody

Clone L13N60

Host Rabbit

Target Species Bovine

Species Reactivity Bovine

Specificity Dopa Decarboxylase Protein

Isotype IgG

Immunogen Recombinant bovine aromatic Dopa decarboxylase

Purification Antigen Affinity Purified

Purity > 90%

Conjugation Unconjugated

Buffer 10 mM HEPES with 150 mM NaCl, 100 µg per ml BSA and 50% glycerol, pH 7.5

Physical State Liquid

Target Information

Dopa decarboxylase (DDC), also known as aromatic-L-amino acid decarboxylase, is a crucial enzyme involved in the biosynthesis of catecholamines and serotonin. It catalyzes the conversion of L-dopa to dopamine, an essential step in the production of several neurotransmitters in the brain. This enzyme is highly expressed in the brain, adrenal glands, and other tissues. DDC is a significant target in the treatment of various neurological and psychiatric disorders, particularly those related to dopamine dysregulation, such as Parkinson's disease.

Target Dopa Decarboxylase Protein

Target Synonym AADC

Taxonomy ID 35356

Gene ID 280762

UniProt ID P27718

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Facchini, Peter J., et al. "Differential and tissue-specific expression of a gene family for tyrosine/dopa decarboxylase in opium poppy." Journal of Biological Chemistry 269.43 (1994): 26684-26690.