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Mouse Anti-Porcine Interferon Regulatory Factor 3 (IRF3) Monoclonal Antibody

Cat. No.VD12N294

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for porcine interferon regulatory factor 3. It is purified by affinity chromatography. It can be applied to WB assay of porcine interferon regulatory factor 3.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone M4N15
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Porcine Interferon Regulatory Factor 3
Isotype IgG
Immunogen Synthesized peptide of interferon regulatory factor 3
Purification Purified by Affinity Chromatography
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol and 0.5% BSA
Physical State Liquid

Target Information

Porcine Interferon Regulatory Factor 3 (IRF3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses, playing a critical role in the innate immune response against DNA and RNA viruses. IRF3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. It is found in an inactive form in the cytoplasm of uninfected cells and becomes activated upon viral infection, double-stranded RNA, or toll-like receptor signaling.

Target Porcine Interferon Regulatory Factor 3
Target Synonym IRF3
Gene ID 396656
UniProt ID Q764M6

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Cao, Tong, et al. "Npro of classical swine fever virus suppresses type III interferon production by inhibiting IRF1 expression and its nuclear translocation." Viruses 11.11 (2019): 998.
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