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Mouse Anti-Chicken CD45 Monoclonal Antibody-[PE]

Cat. No.VD7N249

Product TypeAnimal-targeted Antibodies

Size 0.1 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken CD45. It can be applied to FCM, IHC and IP assays of chicken CD45.

Specifications

Application FCM; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L10N63
Host Mouse
Target Species Chicken
Species Reactivity Chicken
Specificity Chicken CD45
Isotype IgM
Immunogen Chicken bursal lymphocytes
Purity > 90%
Concentration 0.1 mg/mL
Conjugation PE
Preservative and Stabilizer < 0.1% Sodium Azide
Buffer Phosphate Buffered Saline with Stabilizer
Physical State Liquid

Target Information

Chicken CD45, also known as leukocyte common antigen, is a protein tyrosine phosphatase expressed on the surface of various cells in the avian immune system, including T and B lymphocytes. It plays a pivotal role in the regulation of immune cell activation, development, and function by modulating signaling pathways. As a critical component of the immune response in chickens, CD45 is involved in diverse cellular processes such as cell division, cell growth, and the maintenance of immune homeostasis. It is particularly important for the proper functioning of the adaptive immune system, where it contributes to the activation of T cells and B cells by dephosphorylating inhibitory tyrosine residues on signaling molecules.

Target Chicken CD45
Gene ID 386580

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt. Avoid exposure to light and do not freeze.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Härtle, Sonja, et al. "Delineation of chicken immune markers in the era of omics and multicolor flow cytometry." Frontiers in Veterinary Science 11 (2024): 1385400.
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