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Mouse Anti-Porcine Palmitoyl-Protein Thioesterase 1 (PPT1) Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for palmitoyl-protein thioesterase 1. It is affinity purified by protein A. It can be applied to WB and Indirect ELISA assays of palmitoyl-protein thioesterase 1.

Specifications

Application WB; Indirect ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone O13N3

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Palmitoyl-Protein Thioesterase 1

Isotype IgG2

Immunogen Recombinant protein of palmitoyl-protein thioesterase 1

Purification Protein A Purified

Concentration 1 mg/mL

Conjugation Unconjugated

Buffer Phosphate Buffered Saline

Physical State Liquid

Target Information

Porcine palmitoyl-protein thioesterase 1 (PPT1) is a lysosomal enzyme that catalyzes the depalmitoylation of proteins, playing a crucial role in regulating lysosomal function, lipid metabolism, and calcium homeostasis. This enzyme has been implicated in the pathogenesis of various diseases, including neurological disorders and cancer. In pigs, PPT1 is essential for maintaining cellular homeostasis, and its dysfunction can lead to the accumulation of undegarded proteins, which may contribute to disease development.

Target Palmitoyl-Protein Thioesterase 1

Target Synonym CLN1

Gene ID 100517533

UniProt ID A0A4X1VTR6

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Koster, Kevin P., et al. "Depalmitoylation by palmitoyl-protein thioesterase 1 in neuronal health and degeneration." Frontiers in synaptic neuroscience 11 (2019): 25.