Mouse Anti-Canine Nup98 Monoclonal Antibody

Nup98, a component of the nuclear pore complex (NPC), is a nucleoporin that plays a pivotal role in the transport of molecules between the nucleus and the cytoplasm. It is involved in the selective passage of proteins and RNA, ensuring that only properly equipped molecules are allowed to cross the nuclear envelope. Nup98's function is integral to maintaining cellular homeostasis, as it contributes to the regulation of gene expression by facilitating the transport of transcription factors and RNA polymerase. Its interaction with other nucleoporins and transport receptors is essential for the proper functioning of the nuclear transport machinery.