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Mouse Anti-Porcine Internexin Neuronal Intermediate Filament Protein Alpha (INA) Monoclonal Antibody

Cat. No.VD10N65

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for internexin neuronal intermediate filament protein alpha. It is affinity purified by protein A. It can be applied to WB, IHC and Indirect ELISA assays of internexin neuronal intermediate filament protein alpha.

Specifications

Application WB; IHC; Indirect ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone O11N65
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Internexin Neuronal Intermediate Filament Protein Alpha
Isotype IgG2
Immunogen Recombinant protein of internexin neuronal intermediate filament protein alpha
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine internexin neuronal intermediate filament protein alpha (α-Internexin) is a neuron-specific intermediate filament (IF) protein that is expressed in most neurons at the beginning of differentiation and is considered a marker for neuronal IF inclusion disease. It is a type IV IF protein, similar to the neurofilament triplet proteins (NFTPs), and is often co-expressed with them, suggesting its role as a potential fourth subunit of neurofilaments in the central nervous system. α-Internexin can self-polymerize both in vitro and in transfected cells, and it is present in the absence of NFTPs during development and in specific cell types like granule cells in the cerebellum.

Target Internexin Neuronal Intermediate Filament Protein Alpha
Target Synonym 66 kDa neurofilament protein
Gene ID 100153400
UniProt ID A0A4X1TQZ8

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ching, G. Y., et al. "Structure of the gene for the neuronal intermediate filament protein alpha-internexin and functional analysis of its promoter." Journal of Biological Chemistry 266.29 (1991): 19459-19468.
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