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Mouse Anti-Bovine Neutrophil Elastase (ELNE) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine neutrophil elastase. It is purified by affinity chromatography. It can be applied to WB assay of bovine neutrophil elastase.
Specifications
Target Information
Bovine Neutrophil Elastase (NE) is a serine protease encoded by the ELANE gene and belongs to the chymotrypsin family. It is a key enzyme in neutrophils, with potent proteolytic activity that degrades foreign microorganisms and extracellular matrix proteins like elastin and collagen. NE plays a crucial role in host defense, immune response, and inflammation regulation. It is also involved in neutrophil migration and tissue repair. Defects in NE are associated with neutrophil disorders such as cyclic neutropenia.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sommerhoff, C. P., et al. "Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells." The Journal of clinical investigation 85.3 (1990): 682-689.