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Mouse Anti-Porcine Melanophilin (MLPH) Monoclonal Antibody

Cat. No.VD8N343

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for melanophilin. It is affinity purified by protein G. It can be applied to WB, IHC, IF and ELISA assays of melanophilin.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G7N18
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Melanophilin
Isotype IgG1
Immunogen Recombinant protein of melanophilin
Purification Protein G Purified
Concentration 900 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine melanophilin (pMELP) is a protein that is structurally associated with the regulation of melanosome transport within cells, particularly in pigment-producing cells such as melanocytes. This protein plays a crucial role in the biogenesis, transport, and positioning of melanosomes, which are organelles responsible for the production and storage of melanin, the pigment giving color to skin, hair, and eyes. In pigs, melanophilin is instrumental in determining coat color patterns and may be involved in adaptations to different environmental conditions, such as UV radiation protection. The study of pMELP can provide insights into the genetic basis of pigmentation diversity in swine breeds and has implications for the livestock industry, where coat color is a trait of economic and aesthetic significance.

Target Melanophilin
Gene ID 100049680
UniProt ID A0A286ZJY4

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Fukuda, Mitsunori, et al. "Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport." Journal of Biological Chemistry 277.14 (2002): 12432-12436.
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