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Mouse Anti-Porcine Tubulin Polymerization Promoting Protein (TPPP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for tubulin polymerization promoting protein. It is affinity purified by protein A. It can be applied to WB and Indirect ELISA assays of tubulin polymerization promoting protein.
Specifications
Target Information
Porcine tubulin polymerization promoting protein (TPPP), also known as p25, is an important regulator of microtubule dynamics. It interacts directly with tubulin to promote microtubule assembly and stabilize the microtubule network, which is crucial for various cellular processes including cell division, intracellular transport, and maintenance of cell shape. TPPP is a brain-specific protein that is enriched in pathological brain inclusions and has been implicated in neurodegenerative diseases. It can induce the formation of double-walled microtubules and aberrant tubulin aggregates, indicating its significant role in the regulation of the cytoskeleton.
Shipping and Storage
This product is shipped with ice gel packs. Store at -80°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Oláh, Judit, et al. "Interactions of pathological hallmark proteins: Tubulin polymerization promoting protein/p25, β-amyloid, and α-synuclein." Journal of Biological Chemistry 286.39 (2011): 34088-34100.