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Mouse Anti-Chicken Melanoma Cell Adhesion Molecule (MCAM) Monoclonal Antibody

Cat. No.VD7N287

Product TypeAnimal-targeted Antibodies

Size 0.5 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken melanoma cell adhesion molecule. It can be applied to FCM and IP assays of chicken melanoma cell adhesion molecule.

Specifications

Application FCM; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L11N26
Host Mouse
Target Species Chicken
Species Reactivity Chicken; Avian
Specificity Chicken Melanoma Cell Adhesion Molecule
Isotype IgG2
Immunogen Mixture of E15 and E16 thymocytes from chicken embryos
Purity > 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Buffer Borate Buffered Saline, pH 8.2
Physical State Liquid

Target Information

Chicken melanoma cell adhesion molecule, also known as CD146, is a cell surface glycoprotein that is a member of the immunoglobulin superfamily. It is involved in cell-cell adhesion and is expressed in various tissues, including melanoma cells, endothelial cells, and some immune cells. cMCAM plays a role in cellular adhesion, migration, and tissue organization. It is implicated in the maintenance of tissue integrity and has been associated with the regulation of angiogenesis, which is essential for tumor growth and metastasis in melanoma.

Target Chicken Melanoma Cell Adhesion Molecule
Target Synonym CD146; MCAM
Gene ID 448832; 100549798

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wang, Zhaoqing, et al. "CD146, from a melanoma cell adhesion molecule to a signaling receptor." Signal transduction and targeted therapy 5.1 (2020): 148.
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