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Mouse Anti-Porcine Fructose-1,6-Bisphosphatase 1 (FBP1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for fructose-1,6-bisphosphatase 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of fructose-1,6-bisphosphatase 1.
Specifications
Target Information
Porcine fructose-1,6-bisphosphatase 1 (FBP1) is a key regulatory enzyme in gluconeogenesis, catalyzing the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate. This enzyme plays a crucial role in maintaining glucose homeostasis and has been found to be abnormally expressed in various types of cancer, suggesting its significant role in tumorigenesis. The dual functionality of FBP1 as both a metabolic enzyme and a protein phosphatase underscores its potential as a therapeutic target in cancer treatment. Its ability to regulate cellular metabolism and influence gene expression makes it a promising candidate for developing novel cancer therapies. The study of FBP1's role in cancer metabolism is an active area of research, with implications for understanding the molecular mechanisms underlying tumorigenesis and resistance to therapy.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Li, Niu, et al. "Clinical and molecular characterization of patients with fructose 1, 6-bisphosphatase deficiency." International journal of molecular sciences 18.4 (2017): 857.