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Mouse Anti-Porcine Fructose-1,6-Bisphosphatase 1 (FBP1) Monoclonal Antibody

Cat. No.VD10N7

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for fructose-1,6-bisphosphatase 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of fructose-1,6-bisphosphatase 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone O11N7
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Fructose-1,6-Bisphosphatase 1
Isotype IgG2
Immunogen Recombinant protein of fructose-1,6-bisphosphatase 1
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine fructose-1,6-bisphosphatase 1 (FBP1) is a key regulatory enzyme in gluconeogenesis, catalyzing the hydrolysis of fructose-1,6-bisphosphate to fructose-6-phosphate and inorganic phosphate. This enzyme plays a crucial role in maintaining glucose homeostasis and has been found to be abnormally expressed in various types of cancer, suggesting its significant role in tumorigenesis. The dual functionality of FBP1 as both a metabolic enzyme and a protein phosphatase underscores its potential as a therapeutic target in cancer treatment. Its ability to regulate cellular metabolism and influence gene expression makes it a promising candidate for developing novel cancer therapies. The study of FBP1's role in cancer metabolism is an active area of research, with implications for understanding the molecular mechanisms underlying tumorigenesis and resistance to therapy.

Target Fructose-1,6-Bisphosphatase 1
Target Synonym FBP
Gene ID 397038
UniProt ID P00636

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Li, Niu, et al. "Clinical and molecular characterization of patients with fructose 1, 6-bisphosphatase deficiency." International journal of molecular sciences 18.4 (2017): 857.
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