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Mouse Anti-Porcine Transmembrane Protein 175 (TMEM175) Monoclonal Antibody

Cat. No.VD8N204

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for transmembrane protein 175. It is affinity purified by protein A. It can be applied to WB and ELISA assays of transmembrane protein 175.

Specifications

Application WB; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N17
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Transmembrane Protein 175
Isotype IgG1
Immunogen Recombinant protein of transmembrane protein 175
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine transmembrane protein 175 (pTMEM175) is a member of the KATP channel family, which are integral membrane proteins that regulate the flow of potassium ions across cellular membranes. pTMEM175 is primarily expressed in the mitochondria and is involved in the regulation of cellular metabolism and energy homeostasis. It plays a critical role in the maintenance of mitochondrial function, particularly in the context of ATP production and calcium signaling. The protein is also implicated in the regulation of the mitochondrial permeability transition pore, which is a critical pathway in cell death mechanisms. Targeting pTMEM175 in pigs could offer insights into mitochondrial biology and its influence on cellular health and disease processes.

Target Transmembrane Protein 175
Target Synonym Transmembrane protein 175.htmEM175
Gene ID 100622604
UniProt ID A0A8D1HDY9

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Tang, Tuoxian, et al. "Transmembrane protein 175, a lysosomal ion channel related to Parkinson's disease." Biomolecules 13.5 (2023): 802.
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