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Rabbit Anti-Canine SMN Polyclonal Antibody

Product Overview

BioVenic rabbit anti-canine SMN polyclonal antibody is designed to recognize canine SMA. The antibody can be used in the application of immunohistochemistry and western blot. The antibody contributes to broader insights into the genetic and molecular mechanisms of motor neuron diseases, potentially benefiting both veterinary and human medicine.

Specifications

Application IHC; WB

Clonality Polyclonal Antibody

Classification Primary Antibody

Clone A7Y4

Host Rabbit

Target Species Canine

Species Reactivity Canine

Specificity Canine SMN

Purification Immunogen Affinity Purified

Purity ≥ 90% (SDS-PAGE)

Conjugation Unconjugated

Preservative and Stabilizer 0.05 mg Sodium azide (NaN₃), 0.2 mg Na₂HPO₄, 5 mg BSA, 0.9 mg NaCl

Physical State Lyophilized

Target Information

In dogs, SMN is a key protein involved in motor neuron function and maintenance. This is especially important for spinal muscular atrophy (SMA). Understanding the canine SMN and its role in spinal muscular atrophy is critical for veterinary medicine and genetics research.

Target Canine SMN

Target Synonym SMN; SMN1;Survival motor neuron

Gene ID 40389

UniProt ID O02771

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to aliquot and store at -20°C on receipt. (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Friesen, Westley John, et al. "Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN)." Journal of Biological Chemistry 275.34 (2000): 26370-26375.