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Mouse Anti-Canine Ran GTPase Activating Protein 1 (RANGAP1) Monoclonal Antibody

Cat. No.VD11N39

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine ran GTPase activating protein 1. It can be applied to WB, ICC/IF, IHC and FACS assays of canine ran GTPase activating protein 1.

Specifications

Application WB; ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S9N39
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Ran GTPase Activating Protein 1
Isotype IgG2
Immunogen Recombinant protein of ran GTPase activating protein 1
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine ran GTPase activating protein 1 (RANGAP1) is a protein that associates with the nuclear pore complex and plays a pivotal role in the regulation of nuclear transport. It interacts with the Ras-related nuclear protein 1 (RAN), modulating guanosine triphosphate (GTP) binding and exchange, which are crucial for nucleocytoplasmic transport, mitotic spindle formation, nuclear envelope assembly, and heterochromatin assembly. This protein is also implicated in chromosome stability and tumorigenesis, as loss of RANGAP1 can drive chromosome instability and rapid tumorigenesis of osteosarcoma. Targeting RANGAP1 may offer therapeutic strategies for aggressive B-cell lymphoma, highlighting its significance as a potential therapeutic target in canine oncology.

Target Canine Ran GTPase Activating Protein 1
Target Synonym RANGAP1
Gene ID 481234
UniProt ID A0A8C0T0E8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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