Mouse Anti-Porcine Synaptopodin Monoclonal Antibody

Porcine synaptopodin is a structural protein that plays a pivotal role in the formation and maintenance of the actin-rich cytoskeleton in pigs, particularly within the context of the podocyte foot processes in the kidney. Synaptopodin contributes to the organization of the actin filaments, which are crucial for the structural integrity of cells and the regulation of various cellular functions, including cell shape, motility, and the filtration process in the glomeruli of the kidney. This protein is highly expressed in tissues with dynamic actin structures, such as the renal podocytes, where it is essential for the proper functioning of the filtration barrier. Synaptopodin's role in the maintenance of the filtration slits is vital for preventing proteinuria and preserving kidney health.