Mouse Anti-Porcine Translocase of Outer Mitochondrial Membrane 70 (TOM70) Monoclonal Antibody

Porcine translocase of outer mitochondrial membrane 70 (TOM70) is a key component of the mitochondrial protein import machinery, playing a pivotal role in the translocation of precursor proteins into the mitochondrial matrix. TOM70 serves as a receptor for proteins with internal targeting signals, mediating their recognition and transfer to the central receptor, Tom22, which is part of the TOM complex. TOM70 is particularly important for the import of proteins that do not possess a classical N-terminal presequence, which are typically recognized by other receptors such as Tom20. The interaction of TOM70 with its target proteins is essential for their proper localization and function within the mitochondria.