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Mouse Anti-Canine ERK2 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine ERK2. It can be applied to WB, IHC and IP assays of canine ERK2.
Specifications
Target Information
Canine ERK2, or extracellular signal-regulated kinase 2, is a protein kinase that plays a pivotal role in the regulation of cell growth, differentiation, and survival in dogs. It is involved in signal transduction pathways that respond to various stimuli, including growth factors, cytokines, and stress signals. ERK2 is known to phosphorylate and activate transcription factors such as c-Fos and Elk-1, which in turn regulate gene expression related to cell proliferation and differentiation. Recent studies also suggest that ERK2 activity is crucial for proper chromosome alignment during cell division in canine cells, highlighting its importance in maintaining genomic stability.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Naruke, Atsuto, et al. "Tpl2 contributes to IL-1β-induced IL-8 expression via ERK1/2 activation in canine dermal fibroblasts." PLoS One 16.11 (2021): e0259489.