Mouse Anti-Porcine Potassium Voltage-Gated Channel Subfamily A Member 1 (KCNA1) Monoclonal Antibody

Porcine potassium voltage-gated channel subfamily A member 1 (KCNA1), also known as Kv1.1, is a critical component of the voltage-gated potassium channel family. This subfamily of channels plays a significant role in the rapid repolarization of action potentials in neurons and other excitable cells. Kv1.1, in particular, is essential for maintaining proper neuronal excitability and has been implicated in various neurological disorders, such as epilepsy, when its function is compromised. The channel's function is not only limited to the nervous system but also extends to other tissues where it contributes to the regulation of membrane potential and the frequency of action potentials. Kv1.1 forms a heterotetramer with other Kv subunits, creating a channel that is sensitive to voltage changes across the cell membrane. This channel's activity is crucial for the proper timing of electrical signals in the heart and brain, and its dysfunction can lead to serious health consequences.