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Mouse Anti-Canine Retinal Pigment Epithelium 65 kDa Protein (RPE65) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine retinal pigment epithelium 65 kDa protein. It can be applied to WB, ICC/IF, IHC, IHC and FACS assays of canine retinal pigment epithelium 65 kDa protein.
Specifications
Target Information
Canine retinal pigment epithelium 65 kDa protein (RPE65) is an enzyme central to the visual cycle, catalyzing the conversion of all-trans-retinyl ester to 11-cis-retinol, which is essential for the regeneration of visual pigments in both rod and cone photoreceptors. This unique isomerohydrolase activity is vital for maintaining vertebrate vision, and RPE65's role has been confirmed through various studies, dispelling previous beliefs that it was merely a retinoid-binding protein. The protein's function, its modulation by various molecules, and its implications in retinal health are of significant interest in veterinary medicine and gene therapy research, particularly for treating inherited retinal degenerations in dogs.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.