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Mouse Anti-Swine CD205 Monoclonal Antibody
Product Overview
O12H31 monoclonal antibody is specific for Swine CD205, also know as Swine LY75 or DEC-205. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC).
Specifications
Target Information
Cluster of differentiation 205 (CD205), also known as DEC-205 and gp200-MR6 is an endocytic receptor that is expressed at high levels by cortical thymic epithelial cells and by dendritic cell (DC) subsets. Quantitative RT-PCR analysis of the CD205 mRNA profiles in normal porcine tissues and cells showed that thymus and Langerhans cells expressed the highest levels. CD205 plays an important role in antigen uptake for presentation and cross-presentation to T cells.
Shipping and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
References
- Parra-Sánchez, Héctor, et al. "Analysis of Swine Conventional Dendritic Cells, DEC205+ CD172a+/− CADM1+, from Blood and Spleen in Response to PRRSV and PEDV." Viruses 11.11 (2019): 1001.