Mouse Anti-Porcine Proteasome Subunit Beta Type 10 (PSMB10) Monoclonal Antibody

Porcine proteasome subunit beta type 10 (PSMB10) is a crucial component of the 26S proteasome, a cellular complex that degrades unneeded or damaged proteins. PSMB10, as part of the beta subunits within the 20S core particle, contributes to the proteasome's peptidase activity, particularly the chymotrypsin-like activity, which is essential for the proper functioning of the immune system and the cell cycle. This subunit is involved in antigen processing, generating peptides that bind to major histocompatibility complex class I molecules, thereby playing a role in immune surveillance. The importance of PSMB10 is highlighted by its regulation by interferon-gamma, indicating its role in immune responses.