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Mouse Anti-Canine Bardet-Biedl Syndrome 2 (BBS2) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bardet-biedl syndrome 2. It is affinity purified by protein A. It can be applied to WB, IF and ELISA assays of bardet-biedl syndrome 2.
Specifications
Target Information
Canine bardet-biedl syndrome 2 (cBBS2) is a gene in dogs that is associated with bardet-biedl syndrome (BBS), a rare genetic disorder that affects multiple organ systems. BBS is characterized by symptoms such as retinal degeneration leading to blindness, obesity, polydactyly (extra fingers or toes), renal anomalies, and cognitive impairment. cBBS2 encodes a protein that is a component of the BBSome, a complex of proteins that function in the cilia of cells. Cilia are hair-like structures that protrude from the cell surface and are involved in various cellular processes, including the sensing of the cellular environment and the coordination of signaling pathways.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hitti-Malin, Rebekkah J., et al. "A missense variant in the bardet-biedl syndrome 2 gene (BBS2) leads to a novel syndromic retinal degeneration in the shetland sheepdog." Genes 12.11 (2021): 1771.