Rabbit Anti-Chicken Interferon Gamma (IFNg) Polyclonal Antibody-[HRP]

Chicken interferon gamma (IFN-γ) is a vital immunoregulatory cytokine that plays a significant role in the avian immune response, particularly in controlling microbial infections. It is known to upregulate following avian influenza virus (AIV) infection in specific pathogen-free chickens, indicating its involvement in antiviral defense mechanisms. The pre-immune state induced by chIFN-γ can generate an antiviral response against influenza virus, inhibiting the replication of viral RNA and reducing the infectious virus load in chicken embryo fibroblasts. Furthermore, chIFN-γ stimulates the expression of type I IFNs and IFN-stimulated genes (ISGs), enhancing the overall antiviral state against influenza virus infection. This cytokine is essential for both innate and adaptive immune responses against viral infections in chickens, highlighting its importance as a target in avian immunology and disease management.