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Mouse Anti-Bovine Calpastatin Monoclonal Antibody

Cat. No.VD11N194

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine calpastatin. It can be applied to WB, ICC/IF and IHC assays of bovine calpastatin.

Specifications

Application WB; ICC/IF; IHC
Clonality Monoclonal
Classification Primary Antibody
Clone S15N35
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Calpastatin
Isotype IgG2
Immunogen Recombinant protein of calpastatin
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Bovine calpastatin is an endogenous inhibitor of the calpain protease system, which plays a critical role in the regulation of intracellular proteolysis, particularly in the context of meat tenderness and muscle metabolism. It is found in various bovine skeletal muscles and its concentration can significantly impact the efficiency of the calpain system. The balance between calpain II and calpastatin is an important index for the functionality of this proteolytic system, with implications for the conditioning rate of meat from different species and within different muscles of the same species.

Target Bovine Calpastatin
Target Synonym CAST; Calpain inhibitor
Gene ID 281039
UniProt ID P20811

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Cong, Mei, et al. "The bovine calpastatin gene promoter and a new N-terminal region of the protein are targets for cAMP-dependent protein kinase activity." Journal of Biological Chemistry 273.1 (1998): 660-666.
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