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Mouse Anti-Bovine Calpastatin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine calpastatin. It can be applied to WB, ICC/IF and IHC assays of bovine calpastatin.
Specifications
Target Information
Bovine calpastatin is an endogenous inhibitor of the calpain protease system, which plays a critical role in the regulation of intracellular proteolysis, particularly in the context of meat tenderness and muscle metabolism. It is found in various bovine skeletal muscles and its concentration can significantly impact the efficiency of the calpain system. The balance between calpain II and calpastatin is an important index for the functionality of this proteolytic system, with implications for the conditioning rate of meat from different species and within different muscles of the same species.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Cong, Mei, et al. "The bovine calpastatin gene promoter and a new N-terminal region of the protein are targets for cAMP-dependent protein kinase activity." Journal of Biological Chemistry 273.1 (1998): 660-666.