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Rabbit Anti-Bovine Peroxiredoxin 6 (PRDX6) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for bovine peroxiredoxin 6. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine peroxiredoxin 6.
Specifications
Target Information
Bovine peroxiredoxin 6 (PRDX6) is a unique member of the peroxiredoxin family, characterized by its single conserved cysteine residue, distinguishing it as a 1-Cys Prdx. This 25 kDa protein plays a vital role in antioxidant defense, capable of reducing peroxidized membrane phospholipids and exhibiting peroxidase activity towards H2O2 and hydroperoxides. Prdx6 also possesses phospholipase A2 (PLA2) activity, which is significant in phospholipid homeostasis and cell signaling. Its bifunctional nature, with separate active sites for peroxidase and PLA2 activities, makes it crucial for maintaining cellular redox balance and membrane integrity.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Fisher, Aron B., et al. "Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes." Redox biology 14 (2018): 41-46.