Mouse Anti-Chicken Dynamin 1 (DNM1) Monoclonal Antibody

Chicken dynamin 1 (DNM1), similar to its mammalian counterparts, is a highly conserved GTPase enzyme that plays a fundamental role in the regulation of membrane dynamics, particularly in the processes of endocytosis and vesicle trafficking. This protein is crucial for the pinching off of vesicles from the plasma membrane, which is essential for the internalization of nutrients, signaling molecules, and the regulation of cell surface receptors. As a molecular target, chicken DNM1 is significant because of its conserved function in cellular membrane remodeling, impacting a broad range of physiological processes such as neuronal signaling, immune response, and the internalization of pathogens. Dysregulation of DNM1 can lead to various pathological conditions, including neurodegenerative diseases and certain types of cancer.