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Mouse Anti-Porcine Argininosuccinate Synthetase 1 (ASS1) Monoclonal Antibody

Cat. No.VD8N279

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for argininosuccinate synthetase 1. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of argininosuccinate synthetase 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G6N23
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Argininosuccinate Synthetase 1
Isotype IgG1
Immunogen Recombinant protein of argininosuccinate synthetase 1
Purification Protein G Purified
Concentration 1300 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine argininosuccinate synthetase 1 (ASS1) is a crucial enzyme involved in the urea cycle and the synthesis of nitric oxide (NO) in pigs. ASS1 catalyzes the condensation of citrulline with aspartate to form argininosuccinate, which is subsequently converted to arginine and fumarate. This step is essential for the detoxification of ammonia in the body and the maintenance of nitrogen balance. As a key regulatory enzyme in the urea cycle, ASS1 plays a significant role in the metabolism of amino acids and the production of urea, which is the primary means by which pigs excrete excess nitrogen. Additionally, the enzyme contributes to the biosynthesis of nitric oxide, a molecule that is vital for various physiological processes, including vasodilation, immune response, and neurotransmission.

Target Argininosuccinate Synthetase 1
Gene ID 414411
UniProt ID A0A8D1H4Z1

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Sun, Naihui, et al. "Argininosuccinate synthase 1, arginine deprivation therapy and cancer management." Frontiers in pharmacology 13 (2022): 935553.
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