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Mouse Anti-Porcine Argininosuccinate Synthetase 1 (ASS1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for argininosuccinate synthetase 1. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of argininosuccinate synthetase 1.
Specifications
Target Information
Porcine argininosuccinate synthetase 1 (ASS1) is a crucial enzyme involved in the urea cycle and the synthesis of nitric oxide (NO) in pigs. ASS1 catalyzes the condensation of citrulline with aspartate to form argininosuccinate, which is subsequently converted to arginine and fumarate. This step is essential for the detoxification of ammonia in the body and the maintenance of nitrogen balance. As a key regulatory enzyme in the urea cycle, ASS1 plays a significant role in the metabolism of amino acids and the production of urea, which is the primary means by which pigs excrete excess nitrogen. Additionally, the enzyme contributes to the biosynthesis of nitric oxide, a molecule that is vital for various physiological processes, including vasodilation, immune response, and neurotransmission.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sun, Naihui, et al. "Argininosuccinate synthase 1, arginine deprivation therapy and cancer management." Frontiers in pharmacology 13 (2022): 935553.