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Mouse Anti-Swine CD61 Monoclonal Antibody

Cat. No.VD10H24

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

O11H24 monoclonal antibody is specific for Swine CD61, also know as Swine ITGB3 or BDPLT16. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Immunohistochemical (IHC); Immunoprecipitation (IP) and Western Blot (WB).

Specifications

Application FC; IHC; IP; WB

Clonality Monoclonal Antibody

Classification Primary Antibody

Clone O11H24

Host Mouse

Target Species Swine

Species Reactivity Swine; Canine; Bovine; Equine

Specificity Swine CD61

Isotype IgG1

Immunogen Swine peripheral blood mononuclear cells.

Purification Protein A Purified

Purity ≥ 90% (SDS-PAGE)

Concentration 1.0 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.09% Sodium azide (NaN₃)

Buffer Phosphate buffered saline

Physical State Liquid

Target Information

Cluster of differentiation 61 (CD61), also known as Integrin beta-3 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. CD61 functions in thrombus formation by acting as a binding receptor for fibrinogen, fibronectin, plasminogen, prothrombin, von Willebrand factor, and other prothrombotic molecules. Swine CD6 is critical for porcine reproductive and respiratory syndrome virus infection.

Target Swine CD61

Target Synonym ITGB3; BDPLT16; BDPLT2; GP3A; GPIIIa; GT; integrin subunit beta 3; BDPLT24; GT2

Gene ID 397063

UniProt ID Q95JH1

Shipping and Storage

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

References

Hamid, Megat HBA, et al. "Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity." Nature Immunology 25.5 (2024): 834-846.